Researchers are using an epigenetic approach to help restore memory function in AD patients, Charles River Veterinary Pathologist discusses his new book, and is lack of sleep a killer?

It May Be Possible to Restore Memory Function in Alzheimer’s

(Neuroscience News, 1/22/2019, University of Buffalo)

Research published this week in the journal Brain reveals a new approach to Alzheimer’s disease (AD) that may eventually make it possible to reverse memory loss, a hallmark of the disease in its late stages. The team, led by University of Buffalo scientists, found that by focusing on gene changes caused by influences other than DNA sequences — called epigenetics — it was possible to reverse memory decline in an animal model of AD. The research was conducted on mouse models carrying gene mutations for familial AD — where more than one member of a family has the disease — and on post-mortem brain tissues from AD patients.

A Paradigm-changing Tools for Toxicologic Pathology

(SAGE Veterinary Science,1/23/2019)

In this podcast, Editorial Board member Elizabeth McInnes invites author and Charles River Sr. Veterinary Pathologist, Daniel G. Rudmann to discuss his article “The Emergence of Microphysiological Systems (Organs-on-chips) as Paradigm-changing Tools for Toxicologic Pathology” featured in the January 2019 issue of Toxicologic Pathology.

Many not sleeping enough – or well enough – and that’s a killer

(CBS News, 1/24/2019, Lucy Craft)

The U.S. Centers for Disease Control and Prevention says one-third of Americans are not getting the recommended minimum of seven hours a night. In fact, the CDC says our irregular, 24-7, constantly connected lifestyles put us at risk for obesity, cancer, dementia and a shortened lifespan, not to mention hampering job performance. CBS News’ Lucy Craft reports that in Japan, it has become socially acceptable to grab 40 winks just about anywhere, be it on a train, over coffee, even in Parliament — as Prime Minister Shinzo Abe himself has been caught doing on occasion.

 

—Compiled by Social Media Specialist Jillian Scola