The Tragedy of Thalidomide
How a drug that sparked over 10,000 cases of severe limb reduction in children changed the field of toxicology testing. Continue reading
TOX REPORT
Safety and Assessment of Breakthrough Therapies
What’s Holding Microsampling Back?
Misconceptions and myths surrounding the process may be discouraging its use Continue reading
Biting Questions about Zika Models
What can animals tell us about Zika and microcephaly? It depends on the mouse. A report from the Teratology Society meeting Continue reading
Snake and Spider Venom Also Help Save Lives
The creatures we fear are also aiding the development of drugs for diabetes, cancer, neurological disorders and inflammatory diseases. Continue reading
CAR-T’s for Solid Tumors
Scientists study the immunotherapy strategy in brain cancers, plus a real pissing match in the mouse cage. Day Three from SOT. Continue reading
REACH’s Looming Deadline
It’s been 11 years since the EU passed legislation requiring companies to register their use of chemicals by 2018. How’s that going? Day Two of our SOT coverage. Continue reading
Shining a Light on Efficacy and Safety
Molecular imaging has long been a major player in clinical medicine. What about its utility in earlier phases of preclinical drug development? Continue reading
Trending Tools in Toxicology
A period list of methods, tools and people driving research and development. Our scientists present nine tools helping to advance safety assessment. (The list is not ranked.) Continue reading
Sensitive Souls: My Guide to Skin Sensitization Testing
This comprehensive set of in vitro tools helps us predict outcomes of consumer skin care products with almost 100% accuracy. Continue reading
How to Make Microsampling Succeed
Bioanalytical methods need to conform to lower volumes of blood required in efficacy and safety studies. Continue reading