- September 18, 2012 | BY
Most of our communities have access to effective and safe medicines as well as preventative vaccines, a far cry from seven decades ago when polio filled famlies with dread.
- September 10, 2012 | BY
We’re all familiar with the common symptoms of the flu, but what we may not know is that there are a number of complications that can result from it, particularly in young children and the elderly.
- September 7, 2012 | BY
Seth Berkley, an expert on vaccine design, discusses how vaccines of the future might put an end to global threats such as the flu and malaria.
- August 27, 2012 | BY
With its many anatomical, physiological and functional similarities to humans, the miniature pig (minipig, Sus scrofa) has become a viable alternative to non-rodent animal models in nonclinical safety testing.
- August 14, 2012 | BY
Ipilimumab and other cancer biologics like it are based on natural antibodies, slightly changed to give them the long-acting characteristics of the natural form as well as the ability to target proteins on specific cells.
- August 8, 2012 | BY
While photosafety testing has been an important part of preclinical drug development for over 30 years, it’s poorly understood as to the accepted methodologies, when to initiate evaluation, the expectations of the regulatory agencies, and how to interpret results. The lack of clarity in current regulatory guidances, controversy over the interpretation of in vitro assays ...
- July 30, 2012 | BY
Medulloblastoma, a cancer of the central nervous system, is the most common brain malignancy in children, accounting for 15-20% of tumors.
- July 23, 2012 | BY
Even with improved housing and health monitoring, positive serologic or culture findings for microorganisms can and do happen in animal facilities. And as much as an animal facility wants negative laboratory results for all agents on an exclusion list, bacteria, viruses and parasites can sidestep even the best control methodologies, infecting laboratory animal colonies.
- July 16, 2012 | BY
In February of 2012, the Food and Drug Administration (FDA) told makers of cholesterol-lowering statins–a relatively safe drug class that has saved thousands of lives over the past two decades–to add new side effect warnings to their labels. According to the FDA, statin labels must now include the drug’s known association with muscle injury and ...
- July 12, 2012 | BY
When used in a preclinical setting, imaging technologies are helping yield more clinically translatable data to speed drug development.