- January 29, 2013 | BY
This month’s series of articles has focused on the worldwide prevalence of obesity and how it increases the risk for metabolic and respiratory diseases. The underpinning across all of these disorders appears to be activation of the immune system.
It’s well-established that autoimmunity is important in the development of Type 1 diabetes (T1D) in humans, ...
- January 21, 2013 | BY
There is concern now that overweight children have increased odds of getting asthma as well as having a higher severity of the disease.
- January 14, 2013 | BY
Two primary models are used to study obesity, the monogenic and polygenic.
- January 8, 2013 | BY
Two of the most fundamental requirements to our survival are the ability to survive periods of starvation and the capacity to mount an effective response against pathogenic invaders.
- January 2, 2013 | BY
In 1991 there were four states in the United States where 15-19% of the population was obese. When the CDC revised the stats in 2010, every state had an obesity rate over 20%.
- December 17, 2012 | BY
Together, there are nearly 7,000 orphan diseases that impact nearly 30 million Americans.
- December 10, 2012 | BY
Orphan diseases used to be a lonely place in drug development, but with recent analyses showing high profitability potential, support from disease advocacy organizations, and new therapeutic approaches, biopharmaceutical companies are beginning to embrace rare diseases, including Spinal Muscular Atrophy.
- December 5, 2012 | BY
How do pharmaceutical or biotech companies afford to develop orphan drugs, knowing that their development will not be profitable?
- November 26, 2012 | BY
After the recent failures of two Alzheimer’s drugs that target amyloid beta plaques, many have questioned the approach. But new data released in October shows promise for the amyloid hypothesis, provided plaque-targeting drugs are applied early in the disease process.
- November 12, 2012 | BY
Although Alzheimer’s disease (AD) develops differently from person to person, many common symptoms exist.