- May 7, 2012 | BY
It appears the ‘glue’ in our brains has much to do with genius.
- April 16, 2012 | BY
A new research model, developed by our scientists at Discovery Research Services, simply allows rats to grow old and age into their ‘twilight years’, approximately 20 months in case you were wondering.
- April 3, 2012 | BY
ABC News Medical Unit blog features Charles River scientists’ research on lab mice nesting behavior.
- March 20, 2012 | BY
Whether it’s learning to play the guitar, the piano or how to manage people, there are four stages one must journey through in skill development, the final being “The Master”–someone who’s unconsciously competent.
- March 6, 2012 | BY
On February 9th, 2012, the FDA published recommendations for the development of biosimilars. For 60 days, these draft guidance documents will be open for comments and questions, many of which could ultimately affect the final guidance. There are three basic points to consider when developing biosimilars:
(1) Biosimilarity can be demonstrated using an analytical, animal, or ...
- February 27, 2012 | BY
OpenArray®, a PCR platform in chip form the size of a standard microscope slide and containing individual PCR assays in a high-density format is transforming how health monitoring is viewed and implemented.
- February 14, 2012 | BY
Introduction Because cell therapies are mostly human in origin, they are challenging to study in animals (due to tissue rejection). But, these studies are required before starting human trials. Cells are also unlike chemically identical molecules in a standard drug product. That is, they are always a mixture and are always changing in nature, so ...
- January 30, 2012 | BY
While not necessary for most systemic preclinical toxicology studies, the addition of supplemental specialized ocular endpoints may be warranted if a compound belongs to a class known for potential ocular side effects. Supplemental endpoints may also be warranted in the early screening phase in order to weed out the most problematic compounds.
The key is to ...
- January 10, 2012 | BY
In drug development, all small molecules, biologics, medical devices and raw materials must be tested and proven free of endotoxins. Enter the American horseshoe crab.
- January 10, 2012 | BY
Give a child a Rubik’s Cube and motor and math skills develop. Give the same Rubik’s Cube to a rat, and well…nothing happens. It’s totally irrelevant to their development. This is the idea behind behaviorally relevant enrichment.